When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic ...

Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...

Top: Chromosome separate with functioning SMC in two models, line drawing and filled-space. The red and pink dots indicate, respectively, ori on each copy of DNA. Bottom: DNA separating without ...

Red arrows indicate the DNA repair pathways that are known to aid bacterial survival as persisters and gamblers in the presence of fluoroquinolones. Blue color arrow indicates downregulation, while ...

Structural biologists at the University of Wisconsin-Madison today published cryo-electron microscopy structures of the complete bacterial DNA replication restart complex — a molecular machine that le ...