Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
At the scale of individual cells, the human body is constantly in motion. Every second, millions of cells divide, ...
A molecular illustration of the crowded interior and cell envelope of Escherichia coli. (David S. Goodsell, The Scripps Research Institute) To replicate information, life usually has fairly ...
DNA replication and repair mechanisms constitute the foundation of genomic integrity, ensuring that genetic information is faithfully duplicated and maintained across cell generations. Replication ...
Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...