This cleanup appears to take place through autophagy, with myelin debris inside of Schwann cells being carried to lysosomes in a process the authors term "myelinophagy." Using mouse sciatic nerves, ...

Demyelinating diseases, including multiple sclerosis (MS) and Charcot-Marie-Tooth (CMT) disease, present a substantial and escalating burden. Each of these conditions afflicts approximately three ...

How does our nervous system operate so quickly and efficiently? The answer lies in a membranous structure called myelin. Aa Aa Aa All our activities — eating, walking, talking — are controlled by our ...

A research team led by neurobiologist Professor Claire Jacob has identified an important mechanism that can be used to control the restoration of myelin sheaths following traumatic injury and in ...

Durham, NC - A study released today in STEM CELLS may point to a new treatment for myelin-related disorders including Charcot-Marie-Tooth (CMT) disease. The study demonstrates that fibulin 5, a ...

Researchers reveal how cells in the peripheral nervous system (PNS) degrade myelin after nerve injury, a process that fails to occur in the central nervous system (CNS). The study appears in The ...

Researchers reveal how cells in the peripheral nervous system (PNS) degrade myelin after nerve injury, a process that fails to occur in the central nervous system (CNS). The study appears in The ...