Nature

Genome-wide analysis of DNA copy-number changes using cDNA microarrays

The detection of twofold and smaller differences in DNA copy number (twofold in XO versus XX, 1.5-fold in XXX versus XX) is notable. The cDNA elements on our microarrays averaged approximately 1 kb, ...
Nature

Identification of genes involved in hormone-independent prostate cancer by cDNA microarrays, followed by in vivo analysis of selected genes using tissue microarray analysis

Although prostate cancer initially responds and regresses in response to androgen-depletion therapy, most human prostate cancers will re-grow as an androgen-independent tumour. The goal of our study ...
ascopubs.org

A custom cDNA microarray confirms differential transcription factor regulation between neoplastic and non-neoplastic prostatic epithelial cells

The Nottingham Prognostic Index (NPI) applied to 467 patients (pts) with a long-term follow-up that were treated in a single institution No significant financial relationships to disclose. This is an ...
News Medical

Serial Analysis of Gene Expression (SAGE) and DNA Microarray Compared

Serial analysis of gene expression (SAGE) uses mRNA from a sample to create complementary DNA (cDNA) fragments for amplification and sequencing using high-throughput sequencing technology. Credit: ...
ascopubs.org

Global genetic pattern analysis using cDNA microarray-based CGH for prognosis prediction to FAC neoadjuvant and adjuvant chemotherapy in locally advanced breast cancer patients

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2004 ASCO Annual Meeting. This abstract does not include a full text component.
Medscape

Technology Insight: Tuning into the Genetic Orchestra Using Microarrays-Limitations of DNA Microarrays in Clinical Practice

The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling) and ...
PBS

How DNA Microarrays Work

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...